Impact of enhanced haematology palliative care services in patients with myelodysplastic syndrome and acute myeloid leukaemia: study protocol for a randomized controlled trial

Background Patients with acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) suffer from a significant symptom burden psychological, spiritual, social needs comparable to patients solid metastatic malignancy. Referral palliative care services for these haematological remains limited or often confined the last days of life. We pioneered (PC) program integrated standard care. The purpose this trial will study interventions by PC team preliminary results in clinical outcomes. Methods This project is non-blinded, randomized, controlled trial. In study, we examine outcomes MDS/AML when 2nd lines disease treatment failed presence prognostic indicators. group 1, receive associated (i.e., intervention group). contrast, 2, only control group) service on request basis. who join would have complete standardized questionnaire assess their quality life psychological physical symptoms. Results exam impact early enhanced psychosocial both advanced primary family members Hong Kong. Discussion protocol not display any result. If future demonstrate that are effective, they provide plan MDS/AML. Trial registration Kong University/Hospital Authority West Institutional Review Board (HKU/HA HKW IRB). number UW 19-824.